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Preparation H® Reviews

Manufactured by Wyeth Consumer Healthcare, Preparation H is available as a non-prescriptive over-the-counter drug in the form of:





The active ingredients in each share the same major formulation but vary slightly from each other as well as their usage.


How Preparation H Works?

Preparation H has been a brand name for the treatment of hemorrhoids since 1926. Its active ingredient is Phenylephrine which acts to constrict blood vessels.  Because hemorrhoids are caused by inflamed blood vessels, Preparation H effectively shrinks hemorrhoids to attain the relief you need.


The Ointment is formulated with Petrolatum 71.9%, Mineral Oil 14%, Shark Liver Oil 3% and Phenylephrine HCl 0.25% while the Suppositories has Cocoa Butter 85.5%, Shark Liver Oil 3%, and Phenylephrine HCl 0.25%.  Both formulations are intended to provide the following benefits:


Relief of local itching and hemorrhoid discomfort.

Temporary shrinking of hemorrhoidal tissue and relieve burning.

Temporary relief of anorectal discomforts.


The Maximum Strength Cream is formulated with White Petrolatum 15%, Glycerin 14.4%, Pramoxine HCl 1% and Phenylephrine HCl 0.25%. This formulation is aimed at achieving the following benefits:


Temporary relief of pain, soreness and burning.

Relief of local itching and hemorrhoid discomfort.

Temporary shrinking of hemorrhoidal tissue.

Temporary relief of anorectal discomforts.


The Cooling Gel is formulated with Phenylephrine HCl 0.25% and Witch Hazel 50%.  Its chief benefit includes:


Relief of local itching and hemorrhoid discomfort.

Temporary relief of irritation and burning.

Temporary shrinking of hemorrhoidal tissue.

Directions for Use

To achieve its promised relief, follow the instructions on the label as indicated in each form as they vary in usage.   


For your safety, reject the package if the seal in its cap with either an embossed “H” or the name is broken or detached.  


Before administering to children 12 years and below, it is advised that you first consult with your doctor.  


Always cleanse the affected area with moist towel wipes and dry by patting with a soft tissue or cloth before applying.  


In all forms of Preparation H, apply it to your hemorrhoids 4 times every day, in the morning, before sleeping or after every bowel movement.  

Possible Side Effects

There are no reported side effects when using Preparation H but it is advised that you consult with your doctor when you notice any of the following occurring after taking the medication:


Bleeding in the rectal area, aggravated inflammation, redness, pain or irritation in the affected area.


Severe allergic reactions like itching, rashes, hives, breathing difficulties, tightness in the chest, and swelling of the face, lips, tongue or mouth.





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Caution Before And While Using Preparation H

Consult with your doctor before using Preparation H if you have any of the following conditions:

(1) You are taking prescripted medication for depression or high blood pressure;

(2) You are diagnosed with heart disease, high blood pressure, thyroid disease, diabetes, enlarged prostate gland; or

(3) You are pregnant or breast-feeding.


Preparation H in its ointment, gel and cream form are for external use only and its suppositories are for rectal use only.  Keep them all out of reach of children.